Small interfering RNA/silencing RNA (siRNA) is a class of double-stranded, non-coding RNA molecule, 20-25 base pairs in length. As part of the RNA interference pathway, it regulates gene expression by degrading mRNA after transcription, preventing translation.
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The Silencer™ Human Membrane Trafficking siRNA Library is designed for researchers targeting proteins known or predicted to participate in membrane trafficking or remodeling.
Mutations that cause a loss or reduction in gene function can result in the progression to cancer, usually in combination with other genetic changes. Tumor suppressor genes, or anti-oncogenes, can protect cells on the path to becoming cancerous.
Stealth RNAi Predesigned siRNAs are designed to provide robust and long-lasting gene silencing with minimal off-target effects. Stealth RNAi siRNAs are modified synthetic 25-mer RNA duplexes. Our proprietary technology ensures high specificity and stability, making Stealth RNAi siRNAs an ideal choice for researchers seeking reliable and efficient gene knockdown in human, mouse, or rat.
The Silencer™ Select Human Apoptosis siRNA Library provides investigators with a focused siRNA screening platform targeting apoptosis genes and enabling a detailed analysis of the apoptotic signaling pathway.